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Description
Consistent with these observations, single-cell and spatial transcriptomic analyses of AD brains repeatedly reveal downregulation of mitochondrial and bioenergetic gene programs within excitatory neuron populations (Zou et al., 2024)
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Neuroprotective plant extracts exert their effects through multi-target, multi-pathway, providing protection by attenuating inflammation, inhibiting excessive -synuclein (-syn) aggregation, reducing oxidative stress, and preserving essential processes such as synaptic plasticity, neurotransmitter synthesis and release, and neuronal survival
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