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Description
A phase 2, randomized, placebo-controlled study evaluating matrix metalloproteinase-9 inhibitor, andecaliximab, in patients with moderately to severely active Crohns disease
It is delivered to the tissues via chylomicron transport and then to the liver through chylomicron remnant uptake
10.1016/j.resp.2013.03.016 47 KimH
New metabolic inhibitors are being developed, for instance, IACS-010750, an inhibitor of elector complex chain complex 1, a drug currently under phase I clinical trials for AML (ClinicalTrials.gov: NCT02882321) (113)
