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GLP-1 RAS emerge as potent anti-inflammatory molecules that are able to modulate glial activation and cytokine production in several pathologies and conditions in the brain [36]

Apperloo EM, Gorriz JL, Soler MJ, Cigarran Guldris S, Cruzado JM, Puchades MJ, Lopez-Martinez M, Waanders F, Laverman GD, van der Aart-van der Beek A, Hoogenberg K, van Beek AP, Verhave J, Ahmed SB, Schmieder RE, Wanner C, Cherney DZI, Jongs N, Heerspink HJL

Importantly, alongside an enhanced neuroprotective effect, dual receptor agonists may have a more balanced influence on weight loss than single receptor agonists [118]