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However, these drugs, particularly in chronic doses, may actually have deleterious consequences for health and evoke negative side effects [74,76]

A.MacLoughlinR

Deng X, Li S, Kong F, Ruan H, Xu X, Zhang X, et al

This study showed that a subgroup of patients using this innovative de-escalating approach omitting chemotherapy received a pCR response, and around one-third of the patients achieved a promising 3-yeat iDFS from surgery with chemotherapy-free therapy
