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(Note The ATTAIN-1 trial is investigating the efficacy and safety of once daily oral orforglipron in adult participants with obesity or overweight with weight-related comorbidities.) Orforglipron Orforglipron is an orally bioavailable, non-peptide agonist of the GLP-1 receptor

It's believed to help with various disorders

It hits harder and stranger, sometimes to the point where you wonder if youve developed sudden-onset narcolepsy

Compounding the problem is the fact that insurance companies are reluctant to cover these anti-obesity medications, since theyre considered by many to be vanity drugs, even though overwhelming evidence suggests obesity is linked directly to multiple comorbidities