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In another report, two polysaccharide fractions, IA-a and IA-b, stimulated cytokine production and phagocytosis, the mycelial culture significantly upregulated IL-2 and TNF- expression and production in murine and human immune cells, suggesting activation of Th-type cell-mediated immune response in vitro [41]

Goenaga J, Powell GL, Leyrer-Jackson JM, Pina J, Phan S, Prakapenka AV, et al

Moderate risk (high MRD after the first month of treatment, low MRD after the second cycle of chemotherapy)

10.1016/j.mam.2004.09.003 71 NickelsT