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Quercitin upregulates occludin, claudin-1, claudin-3, claudin-4, and claudin-7 in Caco2 cells.[21] Epigallocatechin gallate upregulates IFN- in T84 cells.[22] Berberine upregulates claudin-1 and claudin-2 in HT29/B6 cells.[23] Curcumin upregulates ZO-1, and claudin-1 in CaCo2 cells.[24] Medicinal phototherapeutic herbs such as: Camellia sinensis improves the intestinal barrier, alleviating dysbacteriosis

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Peptide encapsulation technologies, permeation boosters, and enzyme inhibitor co-formulations are all used to get around problems with breakdown and uptake in the intestines

[DOI] [PubMed] [Google Scholar] 144.Koval M