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Pharmacological mTOR inhibition with agents such as rapamycin has been shown to restore autophagic flux, reduce renal inflammation, and protect against kidney damage caused by excessive salt intake in experimental models [207]

According to NHS gastroenterologist Dr Megan Rossi, oral hydration and nutrition remain safer for most people (eatingwell.com)

Ultimately, despite the most extensive research encompassing all major organ systems, and beneficial effects, the full spectrum of beneficial effects necessary to fully validate conceptual toolsranging from cytoprotection to organoprotection and the reestablishment of systemic homeostasisremains elusive