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In contrast to PIONEER REAL Netherlands, the next two most common categories used by people in Italian clinical practice were DPP-4 inhibitors and SGLT2 inhibitors (24.9% and 20.9%, respectively) with sulphonylureas being used by 14.6% of people [36]

Conclusion This study presents a comparative evaluation of DM2 DMTs in preventing DM2-associated AD comorbidity by integrating network pharmacology, MR analysis, and transcriptomic validation

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