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This metabolic adaptation, sometimes called "adaptive thermogenesis," means the body generates less heat as a byproduct of cellular metabolism

Pharmacological agents capable of inhibiting the negative regulator(s) of the signalling pathways are expected to potentiate the action of insulin and leptin and therefore be beneficial for the treatment of Type 2 diabetes and obesity

Oral L-glutamine enhances the circulation of gastrointestinal incretin hormones (glucagon-like peptide-1 (GLP-1) and stimulated insulin release as well as reduced (postprandial) glycemia in diabetes mellitus [14, 15]

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