is semaglutide or tirzepatide better vs for Weight Loss Semaglutide vs tirzepatide vs retatrutide:

It was the first time in the Kaeppeli study (Kaeppeli et al., 2019) that exendin-4 was modified at position 14, where methionine (Met) was replaced by norleucine (Nle), to improve oxidative stability during labelling

While these medications have relatively long half-lives, patients should be advised to take oral DMTs consistently with regard to meals and semaglutide dosing

My doctor said this happens to some people and we could try Wegovy or wait for newer options

doi:10.1002/(SICI)1097-0223(199601)16:1 3.0.CO;2-0 (Case series documenting neonatal intestinal atresia and fetal mortality linked to intra-amniotic methylene blue, foundational evidence for contraindication in pregnancy)