what is the difference between gip and glp 1 Two incretin hormones GLP-1 GIP: Comparison of their actions in insulin secretion and β cell preservation Targeting GLP-1, GIP & GCG

The brain is reward response to food intensifies

Furthermore, GLP-1 shows anti-inflammatory effects on pancreatic islets and adipose tissue [109,110], also in the liver, the vascular system, including aorta and vein endothelial cells, kidney, lung, testis, and skin, by reducing the production of inflammatory cytokines and infiltration of immune cells in the tissues [23,31,56,111]

Key Takeaway: Tirzepatide is unique because it targets two different hormone receptors (GLP-1 and GIP) to support metabolic health and appetite regulation more effectively than single-hormone medications

3.5 Skin side effects Injection site reactions, such as rash, erythema, or itching at the injection site, are common with GLP-1 receptor agonists ( Table 5 , in the Appendix)