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This leads to poor general health, slow growth in children, and weight loss in adults
Literature differentiates peptide-bound copper from inorganic salts
The model was first fitted to the training concentrations (37.5 and 25 M doxorubicin), and then used to simulate the test concentrations (50, 12.5 and 10 M doxorubicin) as a means of blind validation, showing good accordance between the experimental and in silico outputs for all concentrations of doxorubicin

doi: 10.3389/fchem.2025.1698116 Received 03 September 2025 Accepted 15 September 2025 Published 30 September 2025 Volume 13 - 2025 Edited by Ruojun Man, Guangxi Minzu University, China Reviewed by Ramesh Maruthi Chingle, National Institutes of Health (NIH), United States Bing Yang, Nantong University, China Xiaowei Hu, Linyi University, China Updates Copyright 2025 Zhou, Zhang, Lao, Zhou and Zhu