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Although vitamin C is often highlighted for its role in immune system function, it also has many other functions in the human body including as a cofactor in enzymatic reactions, supporting catecholamine production, and aiding tissue repair

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Conditions or disease states (for example Tangiers disease, which is due to a mutation in ABCA1, or LCAT deficiency) that result in lipid poor HDL led to the accelerated catabolism of Apo A-I by the kidney

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