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Am J Physiol Liver Physiol 297:G861G868

Tirzepatide (brand names Mounjaro and Zepbound): A dual-action medication that activates both GLP-1 and GIP receptors, tirzepatide has demonstrated even more impressive weight loss outcomes, with studies showing average weight loss of 15.0% to 20.9% of body weight

Retatrutide may eventually play a role for people with more ambitious weight loss goals once more data is in

Liraglutide has also been shown to significantly modify lipoprotein metabolism, with a reduction of chylomicron production [40, 41] and an increase in chylomicron and low-density lipoprotein (LDL) catabolism [40, 42]