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Experiments using mice have shown that quercetin is able to make a protection against anxiety and depression as well as improve memory by regulating mutually interacting cholinergic and serotonergic systems (Samad et al
Emerging neuroinflammatory modulators (for example TREM2 agonists or cGAS-STING inhibitors) are actively being deployed to quell the secondary glial-driven toxicity triggered by mitochondrial DNA release [92, 96]
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