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Traditionally, it was thought that gut peptides act on VANs to signal to the brain to mediate their metabolic effects, as detailed above for GLP-1 and CCK

This report highlights the therapeutic potential of GLP-2 analogs in a rodent model of chemotherapy-induced gastrointestinal damage

Tirzepatide (brand names Mounjaro and Zepbound): A dual-action medication that activates both GLP-1 and GIP receptors, tirzepatide has demonstrated even more impressive weight loss outcomes, with studies showing average weight loss of 15.0% to 20.9% of body weight

Stop using this medicine and call your healthcare provider right away if you have severe pain in your stomach area (abdomen) that will not go away, with or without vomiting