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It is reported that the safe dose of Zhizi is 610 g, whereas the consumption of 30 g induces significant liver toxicity (Yang et al., 2022) and a single intragastric administration of a specific dose of Juemingzi extract in mice has been shown to cause severe liver and kidney toxicity (Huang et al., 2016
The pooled effect had a favorable outcome in reducing severity and mortality among patients receiving NAC
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On February 27, 2026, US Health and Human Services Secretary Robert F
