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Ineffective erythropoiesis leads to the formation of large, spherical erythrocytes, the lifespan of which is shortened due to their abnormal structure and lower resistance to mechanical damage and other environmental conditions

Oxidized and reduced forms of folate are absorbed to a similar degree

Glutamine also plays a vital role in the synthesis of glutathione (GSH), a potent cellular antioxidant

Amsterdam: Elsevier;1992;632634
