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Hannah Chandler, 35, from California, had tried and failed to lose weight for yearsbut then she discovered a medication that helped her shed 120 pounds in 18 months

In late-stage type 2 diabetes mellitus (T2DM), impaired islet cell function leads to absolute insulin deficiency, thereby disrupting blood glucose homeostasis

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Meanwhile, PA decreased the levels of GLUT4 and phosphorylation of Akt and affected SESN2 expression