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Quick Answer: When semaglutide gets warm beyond recommended storage temperatures, the peptide structure denatures, reducing medication potency and therapeutic effectiveness without necessarily causing visible changes

25 In 2005, exenatide was approved by the U.S

Constipation: Some users may experience the opposite problem difficulty passing stools or a reduced frequency of bowel movements

In the ELIXA trial, Pfeffer et al 27 evaluated the effect of lixisenatide in patients with type 2 diabetes with myocardial infarction or unstable angina admission in the previous 180 days
