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Experiment 2 To evaluate the effects of Ex-4 on brain edema and neurobehavioral function, 30 rats were assigned to five groups: sham, SAH + Vehicle (1 ml sterile 0.9% of NaCl), SAH + Ex-4 (1 g) (1 g in 1 ml sterile 0.9% of NaCl, Sigma-Aldrich, St
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These changes result from the direct effect of GLP-1RAs on proinflammatory cytokines production in monocytes/macrophages as it blocks NF-B, and lowers the formation of pro-inflammatory M1 macrophages
