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This mechanism not only aids in reducing overall calorie intake but also targets stubborn fat deposits in areas like the abdomen, hips, thighs, and arms

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In conclusion, stimulation of human adipocytes in vitro by the GLP-1RA Ex-4 enhanced the expression of irisin at the mRNA and protein levels

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Beyond their metabolic benefits, GLP-1RAs demonstrate immunomodulatory effects, including attenuation of systemic inflammation and modulation of immune cell activity, raising the possibility of relevance to autoimmune conditions such as AITD [9]

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Very elderly, frail adults with limited life expectancy and high sarcopenia risk may suffer more harm than benefit from aggressive weight loss

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