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Additionally, GLP-1 agonists influence gastric emptying, which could interact with psychiatric medication pharmacokinetics, altering their effectiveness or safety, especially those with weight-based dosing

Time to disease progression and time to development of disease-related pain were the initial primary end points, but the primary end point was changed before unblinding based upon survival differences in two previous trials of similar design (described below).[71][Level of evidence A1] After a median follow-up of 34.1 months, the overall mortality was 61.6% in the sipuleucel-T group versus 70.8% in the placebo group (HR death, 0.78
Adjusting Diet and Exercise : Because both medications can impact weight and metabolism, maintaining a healthy diet and exercise routine is beneficial
