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Semaglutide : Selective GLP-1 receptor agonist that suppresses appetite, delays gastric emptying, and enhances glucose-dependent insulin secretion

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In the original clinical trials looking at semaglutide (the GLP-1 in Novo Nordisk's Ozempic and Wegovy) and tirzepatide (in Eli Lilly's Mounjaro and Zepbound), patients gained back most of the weight after

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