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Inflammatory cytokines in ovarian cancer cells, including tumor necrosis factor- (TNF-) and interleukin-1 (IL-1), promote malignant progressionsuch as tumor cell migration and invasionby upregulating the expression of vascular cell adhesion molecule-1 (VCAM-1) and ICAM-1 [79,80,81,82]

These drugs are part of an emerging class of nutrient-stimulated hormone-based therapeutics that act as incretin mimetics, targeting G-proteincoupled receptors such as GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and glucagon, which are crucial in body fat and energy balance regulation

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[DOI] [PubMed] [Google Scholar] [38].Myerson M, Paparodis RD
