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Description
Pyroptosis final stage requires caspase 1 in the conventional pathway and caspase 4/5/11 (caspase 4/5 in humans, caspase 11 in mice) in the noncanonical pathway to cleave GSDMD at D275 into N- and C-termini
Common side effects, like mild swelling or bruising, usually subside within a few days
Redox modulation of NMDA receptor-mediated Ca 2+ flux in mammalian central nerurons
Boosts metabolism: Enhances mitochondrial efficiency and metabolic rate for sustainable energy
