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A dopaminergic basis for working memory, learning and attentional shifting in Parkinsonism
One important factor is homocysteine
Moreover, the transcription factor c-Jun, encoded by the proto-oncogene JUN , upregulates GLS through coordinated transcriptional and post-translational mechanisms
Data show that folic acid supplementation reduces both fasting and postmethionine-load hyperhomocysteinemias, including those in patients with partial congenital defects of CBS and MTHFR
