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They are our main source of fuel, and a key source of the B vitamins involved in energy metabolism

or c) have a BMI between 27 and 30 plus at least one weight-related health condition, such as cardiovascular disease, high blood pressure, or high cholesterol

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The side effects that are known include nausea, vomiting, diarrhea, headache, dizziness, compaction in the gastrointestinal tract, and other GI-related symptoms like acid reflux, bloating, etc
