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Patients must have held a diagnosis of type 2 diabetes mellitus (ICD-10: E11) as well as an HbA1c of at least 6.5%
doi: 10.1056/NEJMoa1603827 38 PfefferMAClaggettBDiazRDicksteinKGersteinHCKberLVet al
It involves communication between peripheral tissues, such as adipose tissue, and central nervous system structures, including the hypothalamus and higher cortical centers
Clinical trials show meaningful weight loss for many people while they are taking the medication, but withdrawal data also shows significant regain after stopping
