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Greenamyre JT
2007 Mar;219(2-3):142-50
5.1.10 Ascorbic acid Ascorbic acid, also known as vitamin C, is an antioxidant that can bind to copper and successfully inhibit the tyrosinase enzyme
These therapeutic effects appear to be mediated through curcumins modulation of key neuromodulators, with particularly noteworthy differential regulation observed between brain and gut tissues: while BDNF and phosphorylated CREB (p-CREB) levels increased in hippocampal tissue, their expression decreased in colonic tissues (Yu et al., 2015)