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Description
Incretin signalling and biased agonism: Basic concepts Both GLP-1 and GIP stimulate insulin secretion from pancreatic beta cells, with GIP also stimulating alpha cells to secrete glucagon (Manchanda et al., 2022)
These gastrointestinal effects were most frequent during dose escalation and typically diminished over time
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However, maintaining open communication with healthcare providers about any unusual symptoms ensures appropriate evaluation and continued safe use of this effective therapeutic agent
